Information Systems Associates Secures Contracts to Perform Services for a Fortune 100 Retailer and a Fortune 1000 Bank

Both Projects to Launch in Third Quarter 2010

PALM CITY, Fla., July 27, 2010 (GLOBE NEWSWIRE) -- Information Systems Associates, Inc. (OTCBB:ISOA - News), a data center optimization software, services and solutions company, today announces it secured contracts to perform services for a Fortune 100 retailer and a Fortune 1000 bank. Both of these projects will launch in the next 15 days and will be competed early in the fourth quarter. These contracts are in addition to current projects including one with a Fortune 100 wireless carrier.

Joe Coschera, the President and Chief Executive Officer of Information Systems Associates, commented, "After a sluggish 2009, it is exciting to see momentum building on numerous fronts including general interest, requests for proposals and signed deals. I attribute much of this success to strong performance from our OSPI V2 (version two) and relationships with leading data center software vendors, as well as an increase in overall IT spending."

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About Information Systems Associates

Information Systems Associates, Inc. (OTCBB:IOSA) based in Palm City, FL. is a leading provider of turnkey data center management solutions with a suite of services including; data center inventory management, data center management software and data center optimization. Its core service utilizes its proprietary technology "OSPI software" (On Site Physical Inventory(R)) which provides a tool set allowing customers to create a highly accurate data set of their current IT inventory and assets. This accurate information is then imported into software that enables businesses to make meaningful decisions on Data Center Management that leads to optimization of resources, cost reductions and significant ROI.

For more information visit our website http://www.isa-inc.net

Safe Harbor

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 (the "Act"). Additionally, words such as "seek," "intend," "believe," "plan," "estimate," "expect," "anticipate" "project" and other similar expressions are forward-looking statements within the meaning of the Act. Some or all of the events or results anticipated by these forward- looking statements may not occur. Factors that could cause or contribute to such differences include the ability of Information System Associates to attract customers for its services, and continue developing innovative datacenter optimization solutions. Further information on Information Systems Associates' risk factors is contained in its filings with the Securities and Exchange Commission, including the Form 10-KSB for the year ended December 31, 2009 and the Form 10-QSB filed March 31, 2010. Information Systems Associates does not undertake any duty nor does it intend to update the results of these forward-looking statements.

Contact:

The WSR Group
Gerald Kieft
772-219-7525
InformationSystemsIR@WallStreetResources.net
www.WallStreetResources.net
www.theWSRgroup.com